3-(4-Bromo­phen­yl)-1-(4-chloro­benz­yl)-1H-pyrazole-5-carbaldehyde

نویسندگان

  • Fu-Rong Li
  • Yu-Juan Zhang
  • Feng-Guang Guo
  • Gui-Yun Duan
  • Yan-Qing Ge
چکیده

The title compound, C(17)H(12)BrClN(2)O, was synthesized by oxidation of [3-(4-bromo-phen-yl)-1-(4-chloro-benz-yl)-1H-pyrazol-5-yl]methanol under mild conditions. The pyrazole ring makes dihedral angles of 3.29 (9) and 74.91 (4)°, respectively, with the bromo-phenyl and chloro-phenyl rings.

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منابع مشابه

3-(4-Bromo­phen­yl)-1-phenyl-1H-pyrazole-4-carbaldehyde

The asymmetric unit of the title compound, C16H11BrN2O, contains two independent mol-ecules with slightly different geometries. The 4-bromo-benzene ring forms dihedral angles of 26.0 (2) and 39.9 (7)° with the pyrazole ring in the two mol-ecules while the phenyl ring is oriented at 19.7 (5) and 7.3 (0)° with respect to the pyrazole ring.

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3-(4-Bromo­phen­yl)-1-phenyl-1H-pyrazole-4-carbaldehyde

In the title compound, C(16)H(11)BrN(2)O, the phenyl and chloro-benzene rings are twisted out of the mean plane of the pyrazole ring, forming dihedral angles of 13.70 (10) and 36.48 (10)°, respectively. The carbaldehyde group is also twisted out of the pyrazole plane [the C-C-C-O torsion angle is 7.9 (3)°]. A helical supra-molecular chain along the b axis and mediated by C-H⋯O inter-actions is ...

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Synthesis and crystal structures of N-substituted pyrazolines.

Four pyrazole compounds, 3-(4-fluorophenyl)-5-phenyl-4,5-dihydro-1H-pyrazole-1-carbaldehyde (1), 5-(4-bromophenyl)-3-(4-fluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbaldehyde (2), 1-[5-(4-chlorophenyl)-3-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone (3) and 1-[3-(4-fluorophenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl]propan-1-one (4), have been prepared by condensing chalcones with hydrazin...

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Ethyl 1-(4-chloro­benz­yl)-3-(4-fluoro­phen­yl)-1H-pyrazole-5-carboxyl­ate

In the title compound, C(19)H(16)ClFN(2)O(2), the pyrazole ring makes dihedral angles of 5.15 (6) and 77.72 (6)°, with the fluoro-phenyl and chloro-phenyl rings, respectively.

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Ethyl 1-(4-chloro­benz­yl)-3-phenyl-1H-pyrazole-5-carboxyl­ate

In the title compound, C(19)H(17)ClN(2)O(2), the pyrazole ring makes dihedral angles of 6.97 (5) and 79.25 (1)°, respectively, with the phenyl and chlorophenyl rings, respectively. In the crystal, C-H⋯O hydrogen bonds are observed.

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عنوان ژورنال:

دوره 68  شماره 

صفحات  -

تاریخ انتشار 2012